e-ISSN: 2148-0842
Spinal ve Periferik Sinir Cerrahisi Bülteni
TND-SPSCG
Spinal ve Periferik Sinir Cerrahisi Bülteni

Spinal ve Periferik Sinir Cerrahisi Bülteni

2024, Sayı 104, No, 1     (Sayfalar: 045-049)

Association of Vitamin D Receptor Gene Polymorphisms with Disc Degeneration

Neslihan ÇAVUŞOĞLU 1 ,Aleyna Gökçen ŞAHİN 1 ,Neşe KESER 1

1 Sağlık Bilimleri Üniversitesi Hamidiye Tıp Fakültesi, Prof. Dr. Mazhar Osman Ruh Sağlığı ve Sinir Hastalıkları Eğitim Araştırma Hastanesi, Beyin ve Sinir Cerrahisi Anabilim Dalı, İstanbul, Türkiye

Görüntüleme: 123
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İndirme : 32

Vitamin D receptor (VDR) gene polymorphism refers to variations or differences in the DNA sequence of the gene encoding VDR. Polymorphisms in the VDR gene may affect a person`s response to vitamin D and susceptibility to various health conditions, including those related to bone health, immune function, and possibly intervertebral disc degeneration (IVDD). This review aimed to examine the relationship between VDR gene polymorphism and IVDD.

Anahtar Kelimeler : Endophenotype, Haplotype, Intervertebral disc degeneration, Single nucleotide polymorphism, Vitamin D receptor